Gizele Thakral was born In Rajasthan, India. One of her parents is a Catholic Christian and the other, a Punjabi. She started modeling in her early teens. Thakral first came into the limelight after participation in Gladrags Model Hunt, where she became one of the top 5 finalists and won the titles of Miss Best Body and Miss Potential. Thakral has also won the title of Miss Rajasthan and featured as a Kingfisher Calendar Model in 2011.
After appearing on two reality TV shows - Survivor India and Welcome Baazi Mehmaan Nawaazi, Thakral participated in the ninth season of Indian reality series Bigg Boss in December 2015.
Her first Bollywood film Kyaa Kool Hain Hum 3, a sex comedy, also featuring Tusshar Kapoor, Aftab Shivdasani, and Mandana Karimi was released on January 22, 2016. She also made a guest appearance in the Sunny Leone starrer sex comedy, Mastizaade, which was also released in the same month.