Samir (Salman Khan) is a flirtatious doctor who falls for every second good-looking female but is not ready for a commitment. As soon as his girlfriend gets serious, he backs off saying he is already married.
Then comes into picture Soniya (Katrina Kaif), a London based model who has wild suicidal tendencies and comes to India for her treatment. Enter Pyaare (Sohail Khan), an aspiring actor who falls in love with Soniya but Soniya falls for her doctor Samir and Samir too responds to her feelings. And this time he is serious!
But then starts the chaos! Samir's married status is revealed to Soniya. But she still loves him and asks the Samir for a divorce for which Samir also agrees. But the problem lies in the fact that a divorce is possible only after marriage. And here Samir is not married at the first place. So now he needs a fake wife to get his divorce and subsequently his love Soniya.
At this instance Naina (Sushmita Sen), a nurse at Samir's hospital comes to his rescue. She poses as his fake wife. But there's another hitch. The nurse also nurses feelings for the Salman though she never voices her love to the doctor.
The film also stars Arshad Warsi and Rajpal Yadav in supporting roles.